Turkey's policies have undergone various ebbs and flows over the past two decades. These policies have been characterized by both friendly relations with neighbors and inference in the internal affairs of certain countries, including Syria. These changes fall under the broader strategic objectives of the Turkish government, which require further examination. This article aims to investigate the reasons behind Turkey's strategic policy shift towards Syria. The significance of Syria's position in Turkey's regional political-security strategy has influenced the Erdogan government's change in strategy. This article addresses the question of the impact of Erdogan's policy shift towards Syria on Turkey's strategic policies in the region. The research findings, based on an explanatory-analytical approach using secondary data, indicate several reasons, including Erdogan's perceptual-psychological nature and personality, his inclination to enhance Turkey's position, the internal political and economic instability, as well as national security concerns, particularly in dealing with Kurdish groups. These factors have constrained the Turkish government to adopt a new policy towards Syria. This shift of policy will change Turkey's strategies in the Middle East and cause it to abandon its neo-Ottomanist policies. The economic instability of Turkey, national security considerations, the long border between the two countries, the issue of the Kurds, terrorism, and the presence of millions of Syrian refugees in Turkey are all significant factors in this strategic shift. Currently, Turkey is more pragmatic in changing its neo-Ottomanist policies.