Today, as in the past the relationships ofcountries in the world are notaffected only by the interaction between them and some of the non-governmental organizations (NGO) are also due to the scope of their duties haveimportant competencies and functions which among them are International Committee of the Red Cross andAmnesty International Committee. These NGOs that passlong time from the beginning of their activities in global levels, can play an important role in many country to country and civil wars and make observance of international humanitarian law during the conflict and the parties are committed to respect international humanitarian law.So the war of attrition andinternal appearance, which is happening now in the Middle East, is the war in Syria. In this study, the role of international non-governmental organizations in line with the action that happens in the world, with a case study of Syria, isbeing investigated. International non-governmental organizations in all activitiesduring the war, ceasefire, prohibits the use of weapons of mass destruction, refugees, prisoners and ... are critically being evaluated that how they provide the fields of development and humanitarian law with their actions, because failure to identify the exact role of these organizations could not meet their important role in the domestic and international levels in the twenty-first century. Due to the inefficiency of public international organizations in many fields, for reasons of political disputes requires the role of these organizations in the world over the past century.