Responsibility to protect as an doctrine has opened its way in some UN Security Councils resolutions. A state has primary responsibility to protect its populations from genocide, war crimes, ethnic cleansing and crimes against humanity. Manifest failure of a state to protect its populations from these crimes transfers responsibility to protect to international community. International community will apply R to P, through the United Nations. Articles 33, 52, 53 and 54 of the UN Charter are regional organizations basis actions for realization of R to P. Regional organizations will help the realization of R to P better than other international organizations because, they are closer to the conflicts that occur in their regions and they are more familiar with those regional issues. Thus, they can also exercise all parts of R to P i.e. responsibility to prevent, responsibility to react and responsibility to rebuild. In other words, mechanisms of regional arrangements for realization of responsibility to protect are a) use of pacific settlements b) military actions. Two aspects of R to P i.e. responsibility to prevent and responsibility to rebuild have a significant role for maintaining, meeting and restoring the peace. In fact, R to P is a practical solution to prevent breach of peace and to help peace building.